According to the United Nations Migration Agency, 38 migrants died when a ship capsized off the coast of Djibouti on a popular route to Yemen.
The International Organization for Migration (IOM) announced Tuesday that 22 more people had been rescued from the shipwreck.
Rescue teams searched for six more migrants who were believed to be on board.
"The International Organization for Migration, can confirm that at least 38 people perished in this latest tragedy, many of them women, children and even babies unfortunately lost their lives when the boat capsized," said Yvonne Ndege, spokesperson for the International Organization for Migration.
"At least 22 people have survived and IOM, in coordination and partnership with local authorities, is helping to respond to the needs of those who survived and help them deal with the trauma that they are facing."
Djibouti is the primary transit country for migrants seeking employment in Gulf nations from Horn of Africa countries such as Ethiopia and Somalia.
The IOM claims that conflict and insecurity, as well as climate change, are major motivators for people to attempt the crossing.
The route is "extremely dangerous" for migrants, who are targeted by traffickers and risk kidnapping, arbitrary arrest, and forced recruitment into warring groups, particularly in Yemen.